Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13067980 | 0.95 | NPC1 (0.53) | NPC1RAB9AKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL23108495 | 0.93 | NPC1 (0.51) | NPC1RAB9AKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL23108796 | 0.93 | NPC1 (0.51) | NPC1RAB9AKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL23108448 | 0.93 | NPC1 (0.51) | NPC1RAB9AKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL23108496 | 0.93 | NPC1 (0.50) | NPC1RAB9AKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL23108447 | 0.92 | NPC1 (0.49) | NPC1RAB9AKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL23108506 | 0.92 | NPC1 (0.49) | NPC1RAB9AKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL29528379 | 0.90 | NPC1 (0.47) | NPC1RAB9AKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL17283237 | 0.90 | NPC1 (0.45) | NPC1RAB9AKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL23108497 | 0.89 | KDM4E (0.47) | NPC1RAB9AKDM4EHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180205019-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2018-07-19 | — | — | US | disclosed |
| US-20180205019-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2018-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180205019-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | SLC25A21, TOE1, SLCO4C1 | NPC1 317/4885RAB9A 1887/4885KDM4E 2499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.