Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 20/20 | 0.83 |
| ▸ | CTSK | P43235 | 9/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17483524 | 1.00 | CTSC (0.83) | CTSCCTSK | |
| SCHEMBL17483525 | 0.96 | CTSC (0.91) | CTSCCTSK | |
| SCHEMBL20384130 | 0.96 | CTSC (0.91) | CTSCCTSK | |
| SCHEMBL17474632 | 0.95 | CTSC (0.90) | CTSCCTSK | |
| SCHEMBL20384072 | 0.95 | CTSC (0.90) | CTSCCTSK | |
| SCHEMBL20384090 | 0.93 | CTSC (0.78) | CTSCCTSK | |
| SCHEMBL20384082 | 0.93 | CTSC (0.78) | CTSCCTSK | |
| SCHEMBL17483526 | 0.93 | CTSC (0.78) | CTSCCTSK | |
| SCHEMBL22642988 | 0.91 | CTSC (1.00) | CTSCCTSK | |
| SCHEMBL16064760 | 0.91 | CTSC (1.00) | CTSCCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3174879-B1 | SUBSTITUTED OXETANES AND THEIR USE AS INHIBITORS OF CATHEPSIN C | BOEHRINGER INGELHEIM INT (DE) | 2018-07-18 | — | — | EP | disclosed |