Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 0.51 |
| ▸ | BRD2 | P25440 | 1/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.48 |
| ▸ | TSPO | P30536 | 1/20 | 0.48 |
| ▸ | EP300 | Q09472 | 1/20 | 0.48 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.48 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20384600 | 0.86 | BRD4 (0.61) | BRD4BRD2ADORA2BTSPOEP300 | |
| SCHEMBL20384416 | 0.86 | BRD4 (0.54) | BRD4BRD2ADORA2BTSPOEP300 | |
| SCHEMBL20384412 | 0.85 | BRD4 (0.69) | BRD4BRD2ADORA2BTSPOEP300 | |
| SCHEMBL20384379 | 0.85 | BRD4 (0.73) | BRD4BRD2ADORA2BTSPOEP300 | |
| SCHEMBL20384252 | 0.84 | BRD4 (0.49) | BRD4 | |
| SCHEMBL20384576 | 0.83 | BRD4 (0.60) | BRD4BRD2ADORA2BTSPOEP300 | |
| SCHEMBL20384573 | 0.81 | BRD4 (0.68) | BRD4BRD2 | |
| SCHEMBL19931274 | 0.80 | BRD4 (0.48) | BRD4 | |
| SCHEMBL15069622 | 0.80 | BRD4 (0.72) | BRD4 | |
| SCHEMBL21658287 | 0.79 | BRD4 (0.53) | BRD4BRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018130174-A1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF IN MEDICINE | 江苏豪森药业集团有限公司 | 2018-07-19 | — | — | WO | disclosed |