Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20385087 | 0.89 | CYP1A2 (0.42) | HTTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL20385152 | 0.88 | HTT (0.47) | HTTPOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20385160 | 0.86 | HTT (0.41) | HTTPOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20385135 | 0.84 | NPC1 (0.44) | HTTPOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20385115 | 0.84 | HTT (0.43) | HTTPOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20385154 | 0.83 | HTT (0.43) | HTTPOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16919552 | 0.83 | HTT (0.47) | HTTPOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20385156 | 0.81 | HTT (0.41) | HTTPOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20385153 | 0.81 | HTT (0.44) | HTTPOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20385133 | 0.81 | HTT (0.41) | HTTPOLBNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2867215-B1 | TETRAZOLE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS | SANIONA AS (DK) | 2018-07-18 | — | — | EP | disclosed |