Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.54 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.54 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.54 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.54 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.54 |
| ▸ | ADCK1 | Q86TW2 | 1/20 | 0.54 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.54 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 10/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 10/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
| ▸ | FLT1 | P17948 | 1/20 | 0.30 |
| ▸ | FLT4 | P35916 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20385594 | 0.88 | MAP2K1 (0.61) | MAP2K1CHEK1MAP2K2MAPK10PRKAG1 | |
| SCHEMBL19050663 | 0.86 | MAP2K1 (0.65) | MAP2K1CHEK1MAP2K2MAPK10PRKAG1 | |
| SCHEMBL20385592 | 0.86 | MAP2K1 (0.60) | MAP2K1CHEK1MAP2K2MAPK10PRKAG1 | |
| SCHEMBL20385591 | 0.85 | MAP2K1 (0.59) | MAP2K1CHEK1MAP2K2MAPK10PRKAG1 | |
| SCHEMBL20385641 | 0.82 | MAP2K1 (0.69) | MAP2K1CHEK1MAP2K2MAPK10PRKAG1 | |
| SCHEMBL19050685 | 0.80 | MAP2K1 (0.72) | MAP2K1CHEK1MAP2K2MAPK10PRKAG1 | |
| SCHEMBL17133279 | 0.80 | MAP2K1 (0.57) | MAP2K1CHEK1MAP2K2MAPK10PRKAG1 | |
| SCHEMBL12869829 | 0.79 | MAP2K1 (0.82) | MAP2K1CHEK1MAP2K2MAPK10PRKAG1 | |
| SCHEMBL12869782 | 0.79 | MAP2K1 (0.82) | MAP2K1CHEK1MAP2K2MAPK10PRKAG1 | |
| SCHEMBL10258182 | 0.79 | MAP2K1 (0.82) | MAP2K1CHEK1MAP2K2MAPK10PRKAG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2714652-B1 | CHIRAL SYNTHESIS OF N-{3,4-DIFLUORO-2-[(2-FLUORO-4-IODOPHENYL)AMINO]-6-METHOXYPHENYL}-1-[2,3-DIHYDROXY-PROPYL]CYCLOPROPANESULFONAMIDES | BAYER IP GMBH (DE) | 2018-07-18 | — | — | EP | disclosed |