Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 19/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20379809 | 0.83 | NAMPT (1.00) | NAMPTGAAKMT2A | |
| SCHEMBL20379288 | 0.78 | NAMPT (0.79) | NAMPTGAAKMT2A | |
| SCHEMBL20389332 | 0.75 | NAMPT (1.00) | NAMPTGAAKMT2A | |
| SCHEMBL20380324 | 0.74 | NAMPT (1.00) | NAMPT | |
| SCHEMBL20379196 | 0.74 | NAMPT (0.80) | NAMPTGAAKMT2A | |
| SCHEMBL20388964 | 0.73 | NAMPT (1.00) | NAMPTGAAKMT2A | |
| SCHEMBL20379209 | 0.73 | NAMPT (1.00) | NAMPT | |
| SCHEMBL11615357 | 0.72 | NAMPT (0.69) | NAMPTGAAKMT2A | |
| SCHEMBL8212768 | 0.72 | NAMPT (0.84) | NAMPTGAAKMT2A | |
| SCHEMBL20379604 | 0.72 | NAMPT (1.00) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018132372-A1 | SMALL MOLECULE ACTIVATORS OF NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) AND USES THEREOF | Sanford Burnham Prebys Medical Discovery Institute (US) | 2018-07-19 | — | — | WO | disclosed |