SCHEMBL20394231

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20394304	0.84	GRM5 (0.47)	PDE10AALDH1A1TDP1KDM4ESMN1; SMN2
	SCHEMBL20394467	0.84	PDE10A (0.47)	PDE10AALDH1A1TDP1SMN1; SMN2ELANE
	SCHEMBL20394324	0.83	PDE10A (0.48)	PDE10AMEN1ALDH1A1KMT2ATDP1
	SCHEMBL20406679	0.79	PDE10A (0.48)	PDE10AALDH1A1TDP1SMN1; SMN2ELANE
	SCHEMBL20755033	0.79	CYP1A2 (0.53)	PDE10ACYP1A2CYP3A4ALOX15HSD17B10
	SCHEMBL20394409	0.79	PDE10A (0.50)	PDE10AALDH1A1TDP1SMN1; SMN2ELANE
	SCHEMBL20394414	0.78	PDE10A (0.49)	PDE10AALDH1A1ELANE
	SCHEMBL20406642	0.77	PDE10A (0.47)	PDE10AALDH1A1TDP1SMN1; SMN2ELANE
	SCHEMBL20406210	0.77	CYP1A2 (0.43)	PDE10ACYP1A2CYP3A4HSD17B10CYP2D6
	SCHEMBL20755042	0.77	PDE10A (0.48)	PDE10AALDH1A1TDP1SMN1; SMN2ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.