SCHEMBL20394502

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18661517	0.88	PDE10A (0.46)	PDE10A
	SCHEMBL20394410	0.86	GRM5 (0.41)	NPSR1PDE10ASCN9ARORC
	SCHEMBL20394435	0.84	FEN1 (0.40)	PDE10AP2RY1
	SCHEMBL20394188	0.83	MAOB (0.39)	PDE10ASCN9A
	SCHEMBL20394456	0.82	GRM5 (0.39)	NPSR1PDE10A
	SCHEMBL20394463	0.82	PDE10A (0.38)	PDE10ASCN9A
	SCHEMBL20394437	0.82	PDE10A (0.39)	POLBPDE10AP2RY1SCN9A
	SCHEMBL20394300	0.82	FEN1 (0.40)	PDE10A
	SCHEMBL18661504	0.82	PDE10A (0.43)	PDE10AGPBAR1
	SCHEMBL20394338	0.82	PDE5A (0.43)	PDE10AGPBAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.