Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 14/20 | 0.46 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL402063 | 0.92 | P2RY1 (0.47) | P2RY1CARM1ABCB1ABCG2NPSR1 | |
| SCHEMBL401218 | 0.88 | P2RY1 (0.49) | P2RY1CARM1ABCB1ABCG2NPSR1 | |
| SCHEMBL545740 | 0.86 | P2RY1 (0.47) | P2RY1CARM1DRD2 | |
| SCHEMBL3204642 | 0.86 | P2RY1 (0.47) | P2RY1CARM1ABCB1ABCG2 | |
| SCHEMBL400451 | 0.86 | P2RY1 (0.50) | P2RY1CARM1ABCB1ABCG2NPSR1 | |
| SCHEMBL29714032 | 0.83 | P2RY1 (0.48) | P2RY1CARM1ABCB1ABCG2NPSR1 | |
| SCHEMBL401768 | 0.83 | P2RY1 (0.48) | P2RY1CARM1ABCB1ABCG2 | |
| SCHEMBL401956 | 0.83 | P2RY1 (0.45) | P2RY1CARM1ABCB1ABCG2NPSR1 | |
| SCHEMBL402147 | 0.82 | P2RY1 (0.44) | P2RY1CARM1ABCB1ABCG2 | |
| SCHEMBL402487 | 0.82 | P2RY1 (0.44) | P2RY1CARM1ABCB1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2862859-B1 | COMPOUNDS, COMPOSITIONS AND METHODS | CYTOKINETICS INC (US) | 2018-07-25 | — | — | EP | disclosed |