⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18647907 | 0.73 | — | — | |
| SCHEMBL14943979 | 0.73 | — | — | |
| SCHEMBL2041553 | 0.62 | — | — | |
| SCHEMBL28860954 | 0.59 | — | — | |
| SCHEMBL2043905 | 0.59 | — | — | |
| SCHEMBL28546930 | 0.59 | — | — | |
| SCHEMBL6990097 | 0.59 | — | — | |
| SCHEMBL27872605 | 0.59 | — | — | |
| SCHEMBL25163 | 0.58 | — | — | |
| SCHEMBL30460641 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105101935-B | Curable composition | 可乐丽则武齿科株式会社 | 2018-02-23 | — | — | CN | disclosed |
| US-20120291159-A1 | Azoline Compounds for Combating Invertebrate Pests | BASF SE (DE) | 2012-11-15 | — | — | US | disclosed |
| WO-2011073444-A2 | AZOLINE COMPOUNDS FOR COMBATING INVERTEBRATE PESTS | BASF SE (DE) | 2011-06-23 | — | — | WO | disclosed |
| EP-1107966-B1 | OXO-PYRIDOIMIDAZOLE-CARBOXAMIDES: GABA BRAIN RECEPTOR LIGANDS | NEUROGEN CORP (US) | 2005-07-27 | — | — | EP | disclosed |
| US-6451809-B2 | COGNITION ACTIVATORS; PSYCHOLOGICAL DISORDERS | NEUROGEN CORPORATION | 2002-09-17 | — | — | US | disclosed |
| US-20010011133-A1 | Oxo-pyridoimidazole-carboxamides: GABA brain receptor ligands | NEUROGEN CORPORATION. | 2001-08-02 | — | — | US | disclosed |
| EP-1107966-A2 | OXO-PYRIDOIMIDAZOLE-CARBOXAMIDES: GABA BRAIN RECEPTOR LIGANDS | NEUROGEN CORPORATION (US) | 2001-06-20 | — | — | EP | disclosed |
| US-6177569-B1 | DIAGNOSIS AND TREATMENT OF ANXIETY, DOWN SYNDROME, DEPRESSION, SLEEP, COGNITIVE AND SEIZURE DISORDERS, OVERDOSE WITH BENZODIAZEPINE DRUGS AND FOR ENHANCEMENT OF ALERTNESS | NEUROGEN CORPORATION | 2001-01-23 | — | — | US | disclosed |
| WO-2000010973-A2 | OXO-PYRIDOIMIDAZOLE-CARBOXAMIDES: GABA BRAIN RECEPTOR LIGANDS | NEUROGEN CORPORATION (US) | 2000-03-02 | — | — | WO | disclosed |
| EP-0498680-A1 | New beta-amino-alpha-hydroxycarboxylic acids and their use | Sankyo Company Limited (JP) | 1992-08-12 | — | — | EP | disclosed |