Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 13/20 | 0.81 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.48 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15534294 | 0.86 | LIMK1 (0.60) | LIMK1CSNK2A2CSNK2BCSNK2A1ALDH1A1 | |
| SCHEMBL16370982 | 0.85 | LIMK1 (0.59) | LIMK1CSNK2A2CSNK2BCSNK2A1ALDH1A1 | |
| SCHEMBL15534269 | 0.85 | LIMK1 (0.59) | LIMK1CSNK2A2CSNK2BCSNK2A1ALDH1A1 | |
| SCHEMBL16385041 | 0.85 | LIMK1 (0.59) | LIMK1CSNK2A2CSNK2BCSNK2A1ALDH1A1 | |
| SCHEMBL16741326 | 0.85 | LIMK1 (0.59) | LIMK1CSNK2A2CSNK2BCSNK2A1ALDH1A1 | |
| SCHEMBL20419781 | 0.83 | LIMK1 (1.00) | LIMK1CSNK2A2CSNK2BCSNK2A1ALDH1A1 | |
| SCHEMBL14625798 | 0.75 | LIMK1 (0.71) | LIMK1ALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL16384794 | 0.74 | LIMK1 (0.59) | LIMK1CSNK2A2CSNK2BCSNK2A1ALDH1A1 | |
| SCHEMBL16741476 | 0.74 | LIMK1 (0.59) | LIMK1CSNK2A2CSNK2BCSNK2A1ALDH1A1 | |
| SCHEMBL15115882 | 0.74 | LIMK1 (0.50) | LIMK1CSNK2A2CSNK2BCSNK2A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018134335-A1 | SUBSTITUTED IMIDAZOPYRIDINPYRIMIDINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-07-26 | — | — | WO | disclosed |