SCHEMBL2039918

SCHEMBL2039918

COC1CNCC[N]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4919096 0.76
SCHEMBL2041735 0.75
SCHEMBL4919518 0.73
SCHEMBL2046096 0.71
SCHEMBL4917535 0.70 CHRM1 (0.35)
SCHEMBL2067724 0.68
SCHEMBL901701 0.67
SCHEMBL1489355 0.67
SCHEMBL42691 0.67
SCHEMBL1461535 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109890209-B Microbicidal oxadiazole derivatives 先正达参股股份有限公司 2021-11-19 CN claimed
EP-3522715-B1 MICROBIOCIDAL OXADIAZOLE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2021-01-20 EP claimed
US-10653146-B2 Microbiocidal oxadiazole derivatives SYNGENTA PARTICIPATIONS AG (CH) 2020-05-19 US claimed
EP-3522715-A1 MICROBIOCIDAL OXADIAZOLE DERIVATIVES Syngenta Participations AG (CH) 2019-08-14 EP claimed
US-20190223442-A1 MICROBIOCIDAL OXADIAZOLE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2019-07-25 US claimed
WO-2018065414-A1 MICROBIOCIDAL OXADIAZOLE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2018-04-12 WO claimed
CN-109890209-B Microbicidal oxadiazole derivatives 先正达参股股份有限公司 2021-11-19 CN disclosed
EP-3522715-B1 MICROBIOCIDAL OXADIAZOLE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2021-01-20 EP disclosed
US-10653146-B2 Microbiocidal oxadiazole derivatives SYNGENTA PARTICIPATIONS AG (CH) 2020-05-19 US disclosed
EP-3522715-A1 MICROBIOCIDAL OXADIAZOLE DERIVATIVES Syngenta Participations AG (CH) 2019-08-14 EP disclosed
US-20190223442-A1 MICROBIOCIDAL OXADIAZOLE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2019-07-25 US disclosed
WO-2018065414-A1 MICROBIOCIDAL OXADIAZOLE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2018-04-12 WO disclosed
US-20120291159-A1 Azoline Compounds for Combating Invertebrate Pests BASF SE (DE) 2012-11-15 US disclosed
US-4044040-A HYPERTENSIVE AGENTS E. R. SQUIBB & SONS, INC. (US) 1977-08-23 US disclosed
US-4032522-A ANTI-GOUT, ANTI-HYPERURICEMIC MERCK & CO., INC. (US) 1977-06-28 US disclosed
US-3984419-A HYPOTENSIVES E. R. SQUIBB & SONS, INC. (US) 1976-10-05 US disclosed
US-3982021-A Compositions for the treatment of coronary diseases containing tetrahydronaphthyloxy-aminopropanols E. R. SQUIBB & SONS, INC. (US) 1976-09-21 US disclosed
US-3951950-A ANTIVIRAL, CARDIOVASCULAR, ANTIINFLAMMATORY E. R. SQUIBB & SONS, INC. (US) 1976-04-20 US disclosed
US-3943149-A HYPOCHOLESTEREMIC, ANTIINFLAMMATORY E. R. SQUIBB & SONS, INC. (US) 1976-03-09 US disclosed
US-3935267-A CARDIOVASCULAR DISORDERS E. R. SQUIBB & SONS, INC. (US) 1976-01-27 US disclosed