Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 13/20 | 0.44 |
| ▸ | IDH2 | P48735 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 5/20 | 0.33 |
| ▸ | FABP5 | Q01469 | 5/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | ITK | Q08881 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21144230 | 0.88 | IDH1 (0.47) | IDH1IDH2FABP4FABP5LCK | |
| SCHEMBL31127261 | 0.88 | IDH1 (0.47) | IDH1IDH2FABP4FABP5LCK | |
| SCHEMBL24061496 | 0.88 | IDH1 (0.47) | IDH1IDH2FABP4FABP5LCK | |
| SCHEMBL21143683 | 0.87 | IDH1 (0.46) | IDH1IDH2FABP4FABP5LCK | |
| SCHEMBL31127045 | 0.87 | IDH1 (0.46) | IDH1IDH2FABP4FABP5LCK | |
| SCHEMBL21165926 | 0.87 | IDH1 (0.41) | IDH1IDH2FABP4FABP5LCK | |
| SCHEMBL19687361 | 0.86 | IDH1 (0.45) | IDH1IDH2FABP4FABP5LCK | |
| SCHEMBL20399597 | 0.85 | IDH1 (0.44) | IDH1IDH2FABP4FABP5LCK | |
| SCHEMBL19686388 | 0.85 | IDH1 (0.44) | IDH1IDH2FABP4FABP5LCK | |
| SCHEMBL19686338 | 0.84 | IDH1 (0.51) | IDH1IDH2FABP4FABP5ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018136917-A1 | POTASSIUM CHANNEL MODULATORS | CADENT THERAPEUTICS, INC. (US) | 2018-07-26 | — | — | WO | disclosed |