SCHEMBL2039969

SCHEMBL2039969

O=C1NC(=S)N/C1=C\c1ccc(-c2ccc(F)c(F)c2)s1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PRF1 P14222 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2015453 1.00 PRF1 (1.00) PRF1
SCHEMBL2015450 1.00 PRF1 (1.00) PRF1
SCHEMBL2038597 0.86 PRF1 (1.00) PRF1
SCHEMBL2038596 0.86 PRF1 (1.00) PRF1
SCHEMBL2038593 0.86 PRF1 (1.00) PRF1
SCHEMBL2022040 0.84 PRF1 (1.00) PRF1
SCHEMBL2022037 0.84 PRF1 (1.00) PRF1
SCHEMBL2022038 0.84 PRF1 (1.00) PRF1
SCHEMBL2038859 0.83 PRF1 (1.00) PRF1
SCHEMBL2043959 0.83 PRF1 (1.00) PRF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011075784-A1 COMPOUNDS, PREPARATIONS AND USES THEREOF PETER MACCALLUM CANCER INSTITUTE (AU) 2011-06-30 WO claimed