Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 18/20 | 0.48 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29447476 | 0.93 | STAT3 (0.43) | STAT3SGMS2 | |
| SCHEMBL20418435 | 0.93 | STAT3 (0.43) | STAT3SGMS2 | |
| SCHEMBL20418605 | 0.92 | STAT3 (0.50) | STAT3SGMS2 | |
| SCHEMBL29447516 | 0.92 | STAT3 (0.50) | STAT3SGMS2 | |
| SCHEMBL20401103 | 0.88 | STAT3 (0.52) | STAT3STAT1 | |
| SCHEMBL20400869 | 0.84 | STAT3 (0.49) | STAT3 | |
| SCHEMBL29447631 | 0.82 | STAT3 (0.41) | STAT3SGMS2 | |
| SCHEMBL29447575 | 0.82 | STAT3 (0.42) | STAT3SGMS2 | |
| SCHEMBL28434204 | 0.82 | STAT3 (0.41) | STAT3SGMS2 | |
| SCHEMBL28439969 | 0.82 | STAT3 (0.42) | STAT3SGMS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018136935-A1 | 2-ARYLSULFONAMIDO-N-ARYLACETAMIDE DERIVATIZED STAT3 INHIBITORS | UNIVERSITY OF HAWAII (US) | 2018-07-26 | — | — | WO | disclosed |