Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 19/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 18/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20401235 | 0.89 | ADORA2A (0.47) | ADORA2AADORA2BADORA1 | |
| SCHEMBL30402180 | 0.85 | ADORA2A (0.45) | ADORA2AADORA2BADORA1 | |
| SCHEMBL20416895 | 0.85 | ADORA2A (0.45) | ADORA2AADORA2BADORA1 | |
| SCHEMBL20401269 | 0.83 | ADORA2A (0.47) | ADORA2AADORA2BADORA1 | |
| SCHEMBL20401425 | 0.81 | ADORA2A (0.46) | ADORA2AADORA2BADORA1 | |
| SCHEMBL20401248 | 0.81 | ADORA2A (0.46) | ADORA2AADORA2BADORA1 | |
| SCHEMBL20401297 | 0.80 | ADORA2A (0.44) | ADORA2AADORA2BADORA1 | |
| SCHEMBL20401358 | 0.80 | ADORA2A (0.54) | ADORA2AADORA2BADORA1 | |
| SCHEMBL20401347 | 0.80 | ADORA2A (0.50) | ADORA2AADORA2BADORA1 | |
| SCHEMBL20401311 | 0.80 | ADORA2A (0.44) | ADORA2AADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018136700-A1 | AZOLOPYRIMIDINE FOR THE TREATMENT OF CANCER-RELATED DISORDERS | ARCUS BIOSCIENCES, INC. (US) | 2018-07-26 | — | — | WO | disclosed |