Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.46 |
| ▸ | GABBR2 | O75899 | 4/20 | 0.43 |
| ▸ | GABBR1 | Q9UBS5 | 4/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 2/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.36 |
| ▸ | ULK1 | O75385 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10303766 | 0.84 | KMT2A (0.70) | KMT2ABRD4ATAD2CDK2PIM1 | |
| SCHEMBL17518644 | 0.84 | KMT2A (0.70) | KMT2ABRD4ATAD2CDK2PIM1 | |
| SCHEMBL29200245 | 0.84 | KMT2A (0.70) | KMT2ABRD4ATAD2CDK2PIM1 | |
| SCHEMBL10007266 | 0.84 | KMT2A (0.70) | KMT2ABRD4ATAD2CDK2PIM1 | |
| SCHEMBL9977770 | 0.84 | KMT2A (0.70) | KMT2ABRD4ATAD2CDK2PIM1 | |
| SCHEMBL16199054 | 0.84 | KMT2A (0.70) | KMT2ABRD4ATAD2CDK2PIM1 | |
| Hydrochloric Acid SCHEMBL28481711 | 0.83 | KMT2A (0.68) | KMT2ABRD4ATAD2CDK2PIM1 | |
| Hydrochloric Acid SCHEMBL28481712 | 0.83 | KMT2A (0.68) | KMT2ABRD4ATAD2CDK2PIM1 | |
| SCHEMBL9977769 | 0.75 | HTT (0.41) | KMT2ABTK | |
| SCHEMBL16120992 | 0.74 | KMT2A (0.41) | KMT2ABRD4ATAD2GABBR2GABBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3141252-B1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | VERTEX PHARMA (US) | 2018-07-25 | — | — | EP | disclosed |