Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 20/20 | 0.84 |
| ▸ | PIK3R1 | P27986 | 10/20 | 0.84 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.84 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.84 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15815961 | 0.92 | PIK3CD (0.83) | PIK3CDPIK3R1PIK3CAPIK3CBPIK3CG | |
| SCHEMBL15817662 | 0.92 | PIK3CD (0.83) | PIK3CDPIK3R1PIK3CAPIK3CBPIK3CG | |
| SCHEMBL15815958 | 0.92 | PIK3CD (0.83) | PIK3CDPIK3R1PIK3CAPIK3CBPIK3CG | |
| SCHEMBL15817660 | 0.92 | PIK3CD (0.83) | PIK3CDPIK3R1PIK3CAPIK3CBPIK3CG | |
| SCHEMBL15816875 | 0.91 | PIK3CD (0.84) | PIK3CDPIK3R1PIK3CAPIK3CBPIK3CG | |
| SCHEMBL15816233 | 0.91 | PIK3CD (0.81) | PIK3CDPIK3R1PIK3CAPIK3CBPIK3CG | |
| SCHEMBL15816215 | 0.91 | PIK3CD (0.81) | PIK3CDPIK3R1PIK3CAPIK3CBPIK3CG | |
| SCHEMBL15816408 | 0.91 | PIK3CD (1.00) | PIK3CDPIK3R1PIK3CAPIK3CBPIK3CG | |
| SCHEMBL15817772 | 0.91 | PIK3CD (0.81) | PIK3CDPIK3R1PIK3CAPIK3CBPIK3CG | |
| SCHEMBL15817301 | 0.91 | PIK3CD (0.81) | PIK3CDPIK3R1PIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2935246-B1 | ISOQUINOLINONE OR QUINAZOLINONE PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | GILEAD CALISTOGA LLC (US) | 2018-07-25 | — | — | EP | disclosed |