Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A3 | P48764 | 14/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2580079 | 0.97 | SLC9A3 (0.74) | SLC9A3 | |
| SCHEMBL2580080 | 0.97 | SLC9A3 (0.74) | SLC9A3 | |
| SCHEMBL16473618 | 0.93 | SLC9A3 (0.69) | SLC9A3 | |
| SCHEMBL13449818 | 0.93 | SLC9A3 (0.69) | SLC9A3 | |
| SCHEMBL13449814 | 0.93 | SLC9A3 (0.69) | SLC9A3 | |
| SCHEMBL20404648 | 0.92 | SLC9A3 (0.71) | SLC9A3 | |
| SCHEMBL24380134 | 0.92 | SLC9A3 (0.67) | SLC9A3 | |
| SCHEMBL13466643 | 0.91 | SLC9A3 (0.67) | SLC9A3 | |
| SCHEMBL13467435 | 0.91 | SLC9A3 (0.67) | SLC9A3 | |
| SCHEMBL16479090 | 0.90 | SLC9A3 (0.66) | SLC9A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3351248-A1 | COMPOUNDS AND METHODS FOR INHIBITING NHE-MEDIATED ANTIPORT IN THE TREATMENT OF DISORDERS ASSOCIATED WITH FLUID RETENTION OR SALT OVERLOAD AND GASTROINTESTINAL TRACT DISORDERS | Ardelyx, Inc. (US) | 2018-07-25 | — | — | EP | disclosed |