Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A3 | P48764 | 14/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16887458 | 0.97 | SLC9A3 (0.75) | SLC9A3 | |
| SCHEMBL16638580 | 0.97 | SLC9A3 (0.75) | SLC9A3 | |
| SCHEMBL24380142 | 0.95 | SLC9A3 (0.73) | SLC9A3 | |
| SCHEMBL13467436 | 0.95 | SLC9A3 (0.73) | SLC9A3 | |
| SCHEMBL16638568 | 0.95 | SLC9A3 (0.72) | SLC9A3 | |
| SCHEMBL15267574 | 0.95 | SLC9A3 (0.72) | SLC9A3 | |
| SCHEMBL16479009 | 0.94 | SLC9A3 (0.71) | SLC9A3 | |
| SCHEMBL16479046 | 0.94 | SLC9A3 (0.71) | SLC9A3 | |
| SCHEMBL20404648 | 0.94 | SLC9A3 (0.71) | SLC9A3 | |
| SCHEMBL24380137 | 0.93 | SLC9A3 (0.70) | SLC9A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3351248-A1 | COMPOUNDS AND METHODS FOR INHIBITING NHE-MEDIATED ANTIPORT IN THE TREATMENT OF DISORDERS ASSOCIATED WITH FLUID RETENTION OR SALT OVERLOAD AND GASTROINTESTINAL TRACT DISORDERS | Ardelyx, Inc. (US) | 2018-07-25 | — | — | EP | disclosed |