Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20406596 | 0.86 | PDE10A (0.44) | PDE10AAHRMEN1KMT2A | |
| SCHEMBL20394384 | 0.86 | PDE10A (0.45) | PDE10AAHRMEN1KMT2A | |
| SCHEMBL20394208 | 0.85 | PDE10A (0.49) | PDE10AAHR | |
| SCHEMBL18661534 | 0.83 | PDE10A (0.47) | PDE10AAHRMEN1KMT2A | |
| SCHEMBL20406784 | 0.79 | PDE10A (0.39) | PDE10A | |
| SCHEMBL20406649 | 0.79 | PDE10A (0.41) | PDE10AAHRMEN1KMT2A | |
| SCHEMBL20394333 | 0.78 | PDE10A (0.43) | PDE10AMEN1KMT2A | |
| SCHEMBL20394162 | 0.77 | PDE10A (0.49) | PDE10AMEN1KMT2A | |
| SCHEMBL20406151 | 0.77 | PDE10A (0.45) | PDE10AMEN1KMT2A | |
| SCHEMBL18661535 | 0.77 | GPBAR1 (0.44) | PDE10AAHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3351533-A1 | BIARYL DERIVATIVE AND MEDICINE CONTAINING SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 2018-07-25 | — | — | EP | disclosed |