Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 6/20 | 0.74 |
| ▸ | BRD4 | O60885 | 3/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20407295 | 0.89 | NR3C2 (0.73) | NR3C2BRD4ARCACNA1BAPBA1 | |
| SCHEMBL19308740 | 0.86 | NR3C2 (0.70) | NR3C2BRD4ARCACNA1BAPBA1 | |
| SCHEMBL16982354 | 0.86 | NR3C2 (0.70) | NR3C2BRD4ARCACNA1BAPBA1 | |
| SCHEMBL16978176 | 0.86 | NR3C2 (0.70) | NR3C2BRD4ARCACNA1BAPBA1 | |
| Mt-3995 SCHEMBL753911 | 0.85 | NR3C2 (1.00) | NR3C2BRD4AR | |
| SCHEMBL753703 | 0.84 | NR3C2 (0.81) | NR3C2BRD4ARCACNA1BAPBA1 | |
| SCHEMBL20068315 | 0.84 | NR3C2 (0.67) | NR3C2BRD4ARCACNA1BAPBA1 | |
| SCHEMBL754718 | 0.83 | NR3C2 (0.80) | NR3C2BRD4AR | |
| SCHEMBL16978177 | 0.83 | NR3C2 (0.65) | NR3C2ARCACNA1BAPBA1PGR | |
| SCHEMBL753732 | 0.83 | NR3C2 (0.78) | NR3C2BRD4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3112354-B1 | METHOD FOR PRODUCING 1,4-BENZOXAZINE COMPOUND | MITSUBISHI TANABE PHARMA CORP (JP) | 2018-07-25 | — | — | EP | disclosed |