Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 2/20 | 0.44 |
| ▸ | RXRB | P28702 | 2/20 | 0.44 |
| ▸ | RXRG | P48443 | 2/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20432640 | 0.89 | HDAC1 (0.54) | HDAC1HDAC6ATMMEN1KMT2A | |
| SCHEMBL17078459 | 0.88 | HDAC1 (0.58) | HDAC1HDAC6ATMMEN1KMT2A | |
| SCHEMBL17078583 | 0.88 | HDAC1 (0.76) | HDAC1HDAC6ATMMEN1KMT2A | |
| SCHEMBL20420893 | 0.88 | HDAC1 (0.47) | HDAC1HDAC6MEN1KMT2AALDH1A1 | |
| SCHEMBL20420986 | 0.85 | HDAC1 (0.78) | HDAC1HDAC6ATMMEN1KMT2A | |
| SCHEMBL20420928 | 0.84 | HDAC1 (0.54) | HDAC1HDAC6MEN1KMT2ARXRA | |
| SCHEMBL20421164 | 0.82 | HDAC1 (0.58) | HDAC1HDAC6ATMMEN1KMT2A | |
| SCHEMBL20420926 | 0.81 | GRIN2B (0.55) | HDAC1HDAC6MEN1KMT2AALDH1A1 | |
| SCHEMBL20421055 | 0.79 | BRD4 (0.44) | HDAC1HDAC6ATMKMT2AALDH1A1 | |
| SCHEMBL20421063 | 0.78 | HDAC1 (0.37) | HDAC1HDAC6RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3116859-B1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2018-08-01 | — | — | EP | disclosed |