Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | S1PR5 | Q9H228 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20421028 | 0.95 | KDM4E (0.51) | HDAC1HDAC6S1PR5KDM4EHTT | |
| SCHEMBL20420981 | 0.87 | HDAC1 (0.60) | HDAC1HDAC6S1PR5KDM4ES1PR1 | |
| SCHEMBL20420931 | 0.87 | HDAC1 (0.60) | HDAC1HDAC6S1PR5KDM4ES1PR1 | |
| SCHEMBL20421057 | 0.87 | HDAC1 (0.60) | HDAC1HDAC6S1PR5KDM4ES1PR1 | |
| SCHEMBL17078507 | 0.87 | HDAC1 (0.68) | HDAC1HDAC6S1PR5KDM4EHTT | |
| SCHEMBL20432838 | 0.87 | HDAC1 (0.68) | HDAC1HDAC6S1PR5KDM4EHTT | |
| SCHEMBL17078471 | 0.87 | MAPT (0.57) | HDAC1HDAC6S1PR5KDM4EHTT | |
| SCHEMBL20421072 | 0.87 | KDM4E (0.52) | HDAC1HDAC6S1PR5KDM4ES1PR1 | |
| SCHEMBL20421006 | 0.86 | HDAC1 (0.48) | HDAC1HDAC6S1PR5S1PR1KDM1A | |
| SCHEMBL20421088 | 0.85 | HDAC1 (0.46) | HDAC1HDAC6S1PR5KDM4ES1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3116859-B1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2018-08-01 | — | — | EP | disclosed |