Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20421196 | 1.00 | HDAC1 (0.55) | HDAC1HDAC6KMT2AACHEMCHR1 | |
| SCHEMBL20420981 | 0.89 | HDAC1 (0.60) | HDAC1HDAC6KMT2AMEN1HDAC4 | |
| SCHEMBL20420931 | 0.89 | HDAC1 (0.60) | HDAC1HDAC6KMT2AMEN1HDAC4 | |
| SCHEMBL20421057 | 0.89 | HDAC1 (0.60) | HDAC1HDAC6KMT2AMEN1HDAC4 | |
| SCHEMBL17078560 | 0.87 | HDAC1 (0.55) | HDAC1HDAC6KMT2AMCHR1MEN1 | |
| SCHEMBL17079039 | 0.87 | HDAC1 (0.73) | HDAC1HDAC6MCHR1HDAC3HDAC4 | |
| SCHEMBL20432829 | 0.87 | HDAC1 (0.73) | HDAC1HDAC6MCHR1HDAC3HDAC4 | |
| SCHEMBL17078551 | 0.87 | HDAC1 (0.55) | HDAC1HDAC6KMT2AMCHR1MEN1 | |
| SCHEMBL17079036 | 0.87 | HDAC1 (0.73) | HDAC1HDAC6MCHR1HDAC3HDAC4 | |
| SCHEMBL20421016 | 0.86 | HDAC1 (0.61) | HDAC1HDAC6KMT2ANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3116859-B1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2018-08-01 | — | — | EP | disclosed |