⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13100977 | 0.85 | CYP1A2 (0.40) | — | |
| SCHEMBL2049499 | 0.78 | — | — | |
| SCHEMBL2778304 | 0.78 | — | — | |
| SCHEMBL9612073 | 0.76 | — | — | |
| Bromide SCHEMBL11107539 | 0.75 | — | — | |
| SCHEMBL12360492 | 0.75 | HRH3 (0.37) | — | |
| SCHEMBL17354721 | 0.75 | HRH3 (0.37) | — | |
| SCHEMBL16020983 | 0.75 | HRH3 (0.37) | — | |
| SCHEMBL3768026 | 0.75 | — | — | |
| SCHEMBL23666391 | 0.69 | DRD1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12037357-B2 | Compounds for activating invariant natural killer T-cells and methods of use in eliminating inflammatory senescent cells | DECIDUOUS THERAPEUTICS, INC. (US) | 2024-07-16 | — | — | US | disclosed |
| US-20240025936-A1 | COMPOUNDS FOR ACTIVATING INVARIANT NATURAL KILLER T-CELLS AND METHODS OF USE IN ELIMINATING INFLAMMATORY SENESCENT CELLS | DECIDUOUS THERAPEUTICS, INC. (US) | 2024-01-25 | — | — | US | disclosed |
| EP-3386974-B1 | WATER-SOLUBLE TRIAZAPYRIDINOPHANE-BASED COMPLEXING AGENTS AND CORRESPONDING FLUORESCENT LANTHANIDE COMPLEXES | CISBIO BIOASSAYS (FR) | 2020-02-05 | — | — | EP | disclosed |
| EP-2838857-B1 | A PELLET AND A METHOD OF MANUFACTURING GLASS | SIBELCO UK LTD (GB) | 2019-05-22 | — | — | EP | disclosed |
| US-10036093-B2 | Heterojunction elevated-temperature photoelectrochemical cell | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2018-07-31 | — | — | US | disclosed |