Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18468604 | 1.00 | ELANE (0.51) | ELANEKMT2AATMHSD17B10LMNA | |
| SCHEMBL28126189 | 0.95 | ELANE (0.56) | ELANEKMT2AATMHSD17B10LMNA | |
| SCHEMBL21417777 | 0.91 | ELANE (0.48) | ELANEKMT2AATMHSD17B10LMNA | |
| SCHEMBL17750884 | 0.88 | ELANE (0.42) | ELANEKMT2AATMHSD17B10LMNA | |
| SCHEMBL12872192 | 0.88 | ELANE (0.62) | ELANEKMT2AATMHSD17B10LMNA | |
| SCHEMBL803168 | 0.88 | ELANE (0.62) | ELANEKMT2AATMHSD17B10LMNA | |
| SCHEMBL17433304 | 0.88 | ELANE (0.62) | ELANEKMT2AATMHSD17B10LMNA | |
| SCHEMBL18436419 | 0.87 | ELANE (0.43) | ELANEKMT2AATMHSD17B10SMN1; SMN2 | |
| SCHEMBL18823077 | 0.87 | ELANE (0.51) | ELANEKMT2AATMHSD17B10LMNA | |
| SCHEMBL21469985 | 0.87 | ELANE (0.41) | ELANEKMT2AATMHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4306615-A1 | LIQUID-CRYSTAL MEDIUM | Merck Patent GmbH (DE) | 2024-01-17 | — | — | EP | disclosed |
| EP-3933009-A1 | LIQUID CRYSTAL MEDIUM | Merck Patent GmbH (DE) | 2022-01-05 | — | — | EP | disclosed |
| EP-2957618-B1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2018-08-01 | — | — | EP | disclosed |