Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 8/20 | 0.48 |
| ▸ | PDE4A | P27815 | 3/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.48 |
| ▸ | RORC | P51449 | 7/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29895375 | 0.87 | PDE4B (0.50) | PDE4BPDE4APDE4CPDE4DRORC | |
| SCHEMBL19241609 | 0.87 | PDE4B (0.50) | PDE4BPDE4APDE4CPDE4DRORC | |
| SCHEMBL18872922 | 0.84 | APP (0.42) | PDE4BPDE4APDE4CPDE4DCSF1R | |
| SCHEMBL17559323 | 0.80 | PDE4B (0.49) | PDE4BPDE4APDE4CPDE4DCSF1R | |
| SCHEMBL7384901 | 0.78 | PDE4B (0.66) | PDE4BPDE4APDE4CPDE4DCSF1R | |
| SCHEMBL7380651 | 0.78 | PDE4B (0.66) | PDE4BPDE4APDE4CPDE4DCSF1R | |
| SCHEMBL5368892 | 0.78 | PDE4B (0.66) | PDE4BPDE4APDE4CPDE4DCSF1R | |
| SCHEMBL20429759 | 0.77 | PDE4B (0.52) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL17559322 | 0.75 | PDE4B (0.54) | PDE4BPDE4APDE4CPDE4DCSF1R | |
| SCHEMBL3905579 | 0.75 | PDE4B (0.59) | PDE4BPDE4APDE4CPDE4DCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3189044-B1 | CRYSTALLINE (2S)-3-[(3S,4S)-3-[(1R)-1-HYDROXYETHYL]-4-(4-METHOXY-3-{[1-(5-METHYLPYRIDIN-2-YL)AZETIDIN-3-YL]OXY}PHENYL) -3-METHYLPYRROLIDIN-1-YL]-3-OXOPROPANE-1,2-DIOL | LILLY CO ELI (US) | 2018-08-01 | — | — | EP | disclosed |