Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 12/20 | 0.63 |
| ▸ | SGPL1 | O95470 | 7/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20431330 | 0.84 | SMO (0.61) | SMOSGPL1 | |
| SCHEMBL20431427 | 0.84 | SMO (0.61) | SMOSGPL1 | |
| SCHEMBL20431404 | 0.84 | SMO (0.64) | SMO | |
| SCHEMBL20431292 | 0.81 | SMO (0.62) | SMOSGPL1 | |
| SCHEMBL20431298 | 0.81 | SMO (0.42) | SMO | |
| SCHEMBL20431266 | 0.81 | SMO (0.58) | SMOSGPL1 | |
| SCHEMBL20431317 | 0.78 | MEN1 (0.40) | SMO | |
| SCHEMBL3598111 | 0.78 | SMO (1.00) | SMOSGPL1 | |
| SCHEMBL3599997 | 0.78 | SMO (1.00) | SMOSGPL1 | |
| SCHEMBL3598043 | 0.77 | SMO (1.00) | SMOSGPL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2137162-B1 | ORGANIC COMPOUNDS AND THEIR USES | NOVARTIS AG (CH) | 2018-08-01 | — | — | EP | disclosed |