Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 20/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20433030 | 0.92 | ATR (0.52) | ATR | |
| SCHEMBL20433474 | 0.92 | ATR (0.57) | ATR | |
| SCHEMBL20433721 | 0.86 | ATR (0.54) | ATR | |
| SCHEMBL3055543 | 0.83 | ATR (0.57) | ATR | |
| SCHEMBL19672728 | 0.79 | ATR (0.67) | ATR | |
| SCHEMBL19672717 | 0.79 | ATR (0.58) | ATR | |
| SCHEMBL13138313 | 0.78 | ATR (0.62) | ATR | |
| SCHEMBL20433476 | 0.78 | ATR (0.57) | ATR | |
| SCHEMBL16424854 | 0.78 | ATR (0.62) | ATR | |
| SCHEMBL16424866 | 0.78 | ATR (0.59) | ATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3354650-A1 | COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE | Vertex Pharmaceuticals Incorporated (US) | 2018-08-01 | — | — | EP | disclosed |