Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24681817 | 0.74 | ATR (0.63) | ATR | |
| SCHEMBL13347142 | 0.72 | ATR (0.54) | ATR | |
| SCHEMBL20433148 | 0.72 | ATR (0.51) | ATR | |
| SCHEMBL24681790 | 0.71 | ATR (0.58) | ATR | |
| SCHEMBL13138043 | 0.63 | ATR (0.81) | ATR | |
| SCHEMBL13138223 | 0.63 | ATR (1.00) | ATR | |
| SCHEMBL20433179 | 0.62 | ATR (0.58) | ATR | |
| SCHEMBL24248192 | 0.61 | ATR (0.57) | ATR | |
| SCHEMBL20433209 | 0.61 | ATR (0.47) | ATR | |
| SCHEMBL19672802 | 0.60 | ATR (0.60) | ATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3354650-A1 | COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE | Vertex Pharmaceuticals Incorporated (US) | 2018-08-01 | — | — | EP | disclosed |