Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 20/20 | 0.89 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2483377 | 0.94 | ATR (1.00) | ATR | |
| SCHEMBL13138184 | 0.94 | ATR (0.90) | ATR | |
| SCHEMBL2508834 | 0.93 | ATR (0.85) | ATR | |
| SCHEMBL13138271 | 0.92 | ATR (0.87) | ATR | |
| SCHEMBL13138241 | 0.89 | ATR (0.82) | ATR | |
| SCHEMBL13138038 | 0.87 | ATR (0.78) | ATR | |
| SCHEMBL2511633 | 0.87 | ATR (1.00) | ATR | |
| SCHEMBL2486702 | 0.86 | ATR (0.76) | ATR | |
| SCHEMBL2508892 | 0.85 | ATR (0.81) | ATR | |
| SCHEMBL13137897 | 0.85 | ATR (0.81) | ATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4059932-A1 | COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE | Vertex Pharmaceuticals Incorporated (US) | 2022-09-21 | — | — | EP | disclosed |
| EP-3354650-A1 | COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE | Vertex Pharmaceuticals Incorporated (US) | 2018-08-01 | — | — | EP | disclosed |