SCHEMBL204417

SCHEMBL204417

C=CC(=O)OCCC[Si](Cl)(Cl)Cl

nearest known ligand 0.63

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.63
ALDH1A1 P00352 4/20 0.63
CYP3A4 P08684 2/20 0.63
HPGD P15428 1/20 0.57
TP53 P04637 3/20 0.52
HIF1A Q16665 3/20 0.52
HSD17B10 Q99714 1/20 0.52
THRB P10828 2/20 0.40
MAPK1 P28482 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
ATM Q13315 1/20 0.36
HCAR2 Q8TDS4 3/20 0.32
MAPT P10636 1/20 0.32
RAB9A P51151 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2781110 0.94 TSHR (0.67) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL23321684 0.92 TSHR (0.70) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL23321920 0.92 TSHR (0.70) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL23322202 0.92 TSHR (0.70) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL23321687 0.92 TSHR (0.70) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL23321632 0.92 TSHR (0.70) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL23321736 0.92 TSHR (0.70) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL23321915 0.92 TSHR (0.70) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL23321546 0.92 TSHR (0.70) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL23321904 0.92 TSHR (0.70) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1041 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119751778-A Improved polycarboxylate superplasticizer and preparation method and application thereof 南宁兴典混凝土有限责任公司 2025-04-04 CN claimed
CN-117924836-A High-flame-retardance cable insulating material and preparation method thereof 常州工学院 2024-04-26 CN claimed
US-11955603-B2 Composite electrolytes QUANTUMSCAPE BATTERY, INC. (US) 2024-04-09 US claimed
EP-3861039-B1 HYDROGEL COMPOSITIONS OPHTALMIC CIE (FR) 2023-11-01 EP claimed
US-11597789-B2 Materials for hydrophilic interaction chromatography and processes for preparation and use thereof for analysis of glycoproteins and glycopeptides WATERS TECHNOLOGIES CORPORATION (US) 2023-03-07 US claimed
CN-114685711-B Modified flocculant and preparation method thereof 东营市北陆生物科技有限公司 2022-08-30 CN claimed
CN-114685711-A Modified flocculant and preparation method thereof 东营市北陆生物科技有限公司 2022-07-01 CN claimed
US-20220077495-A1 COMPOSITE ELECTROLYTES QUANTUMSCAPE BATTERY, INC. 2022-03-10 US claimed
CN-107710455-B Composite electrolyte 昆腾斯科普电池公司 2021-12-17 CN claimed
US-20210332174-A1 HYDROGEL COMPOSITIONS OPHTALMIC COMPAGNIE (FR) 2021-10-28 US claimed
US-20020123592-A1 Organic-inorganic hybrids surface adhesion promoter ZENASTRA PHOTONICS INC. 2002-09-05 US claimed
US-5990333-A A THERMOSETTING POLYAMIDE OF A DICARBOXYLIC ACID AND A POLYAMINE, E.G. DIETHYLENETRIAMINE MODIFIED BY A HYDROLYZABLE REACTIVE SILANETRIOL; SIZING CELLULOSE, FIBERS AND PAPER SIZING; WET AND DRY STRENGTH OF PAPER PULP; CREPING ADHESIVE HERCULES INCORPORATED (US) 1999-11-23 US claimed
EP-0637902-B1 Metallic foil with adhesion promoting layer GOULD ELECTRONICS INC (US) 1999-03-31 EP claimed
EP-0814108-A1 Silyl-linked polyamidoamines and their preparation HERCULES INCORPORATED (US) 1997-12-29 EP claimed
EP-0593297-B1 Resin composition for coating and paint HITACHI CHEMICAL CO LTD (JP) 1997-04-16 EP claimed
US-5539051-A ACRYLATE RESIN AND ADDITION TYPE RESIN WITH PENDANT SILICON CONTAINING GROUPS, FOR CONCRETE, MASONRY, NONSTAINING HITACHI CHEMICAL COMPANY CO., LTD. (JP) 1996-07-23 US claimed
CN-1106977-A Metallic foil with adhesion promoting layer COULD ELECTRONICS INC (US) 1995-08-16 CN claimed
EP-0637902-A1 Metallic foil with adhesion promoting layer GOULD ELECTRONICS INC. (US) 1995-02-08 EP claimed
EP-0593297-A1 Resin composition for coating and paint HITACHI CHEMICAL CO., LTD. (JP) 1994-04-20 EP claimed
US-5023159-A Encapsulated electrophotographic toner compositions XEROX CORPORATION (US) 1991-06-11 US claimed