Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN1 | Q92952 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3552335 | 0.77 | HDAC3 (0.33) | KCNN1 | |
| Trifluoroacetic Acid SCHEMBL2160769 | 0.63 | CES1 (0.34) | KCNN1 | |
| SCHEMBL12562651 | 0.63 | — | — | |
| Trifluoroacetic Acid SCHEMBL11674761 | 0.63 | — | — | |
| Trifluoroacetic Acid SCHEMBL27442777 | 0.63 | CA4 (0.36) | — | |
| Trifluoroacetic Acid SCHEMBL8201466 | 0.63 | — | — | |
| Trifluoroacetic Acid SCHEMBL5816346 | 0.63 | — | — | |
| Trifluoroacetic Acid SCHEMBL11687890 | 0.61 | CA4 (0.35) | — | |
| Trifluoroacetic Acid SCHEMBL11412009 | 0.61 | CA4 (0.35) | — | |
| Trifluoroacetic Acid SCHEMBL11691439 | 0.61 | CA4 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2513098-A1 | AMINOPYRIMIDINES AS SYK INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011075515-A1 | AMINOPYRIMIDINES AS SYK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2011-06-23 | — | — | WO | disclosed |