Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.68 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.56 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | OGA | O60502 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 6/20 | 0.41 |
| ▸ | SORD | Q00796 | 1/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17626798 | 0.82 | HRH3 (0.64) | HRH3HRH4CDK1ROCK1SORD | |
| SCHEMBL3784623 | 0.81 | HRH3 (1.00) | HRH3HRH4OGAROCK1PRKCQ | |
| SCHEMBL17626780 | 0.81 | HRH3 (0.81) | HRH3HRH4OGAROCK1MAP3K14 | |
| SCHEMBL22616978 | 0.80 | HRH3 (0.73) | HRH3HRH4OGAROCK1 | |
| Hydrochloric Acid SCHEMBL3781024 | 0.80 | HRH3 (0.97) | HRH3HRH4OGAROCK1PRKCQ | |
| SCHEMBL13018541 | 0.79 | HRH3 (0.60) | HRH3HRH4CDK1ROCK1PRKCQ | |
| SCHEMBL28555574 | 0.77 | HRH3 (0.57) | HRH3HRH4CDK1SORDPRKCQ | |
| SCHEMBL20507928 | 0.77 | HRH3 (0.57) | HRH3HRH4BTK | |
| SCHEMBL17626748 | 0.77 | HRH3 (0.71) | HRH3HRH4OGAROCK1SORD | |
| SCHEMBL14880196 | 0.77 | HRH3 (0.71) | HRH3HRH4OGAROCK1SORD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3355699-A1 | BICYCLIC COMPOUND AND USE THEREOF FOR INHIBITING SUV39H2 | OncoTherapy Science, Inc. (JP) | 2018-08-08 | — | — | EP | disclosed |