Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 4/20 | 0.44 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20446587 | 0.92 | KLKB1 (0.45) | KLKB1PARP1F2 | |
| SCHEMBL20446531 | 0.88 | KLKB1 (0.47) | KLKB1PARP1F2 | |
| SCHEMBL20446458 | 0.88 | KLKB1 (0.47) | KLKB1PARP1F2 | |
| SCHEMBL20446508 | 0.87 | KLKB1 (0.47) | KLKB1PARP1 | |
| SCHEMBL20446462 | 0.84 | KLKB1 (0.45) | KLKB1F2 | |
| SCHEMBL20446530 | 0.83 | KLKB1 (0.38) | KLKB1PARP1F2 | |
| SCHEMBL20446615 | 0.83 | KLKB1 (0.42) | KLKB1 | |
| SCHEMBL20584676 | 0.82 | KLKB1 (0.66) | KLKB1 | |
| SCHEMBL20446540 | 0.80 | KLKB1 (0.45) | KLKB1PARP1 | |
| SCHEMBL17064776 | 0.80 | KLKB1 (0.41) | KLKB1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3355890-A1 | HUMAN PLASMA KALLIKREIN INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2018-08-08 | — | — | EP | disclosed |