Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 3/20 | 0.37 |
| ▸ | MPI | P34949 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2044767 | 1.00 | KDM4E (0.44) | KDM4EMAPTALDH1A1KMT2AATM | |
| SCHEMBL2049445 | 0.91 | KDM4E (0.48) | KDM4EMAPTALDH1A1KMT2AHSD11B1 | |
| SCHEMBL2049444 | 0.91 | KDM4E (0.48) | KDM4EMAPTALDH1A1KMT2AHSD11B1 | |
| SCHEMBL9900361 | 0.86 | KDM4E (0.44) | KDM4EMAPTALDH1A1KMT2AHSD11B1 | |
| SCHEMBL9900358 | 0.86 | KDM4E (0.44) | KDM4EMAPTALDH1A1KMT2AHSD11B1 | |
| SCHEMBL214492 | 0.85 | MAPT (0.49) | KDM4EMAPTALDH1A1KMT2AHSD11B1 | |
| SCHEMBL9898197 | 0.85 | KDM4E (0.43) | KDM4EMAPTALDH1A1KMT2AHSD11B1 | |
| SCHEMBL9898198 | 0.85 | KDM4E (0.43) | KDM4EMAPTALDH1A1KMT2AHSD11B1 | |
| SCHEMBL2052836 | 0.83 | KDM4E (0.46) | KDM4EMAPTALDH1A1KMT2ACA1 | |
| SCHEMBL2052834 | 0.83 | KDM4E (0.46) | KDM4EMAPTALDH1A1KMT2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8338544-B2 | Polymers functionalized with polyoxime compounds and methods for their manufacture | BRIDGESTONE CORPORATION (JP) | 2012-12-25 | — | — | US | claimed |
| US-20110152449-A1 | POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE | BRIDGESTONE CORPORATION (JP) | 2011-06-23 | — | — | US | claimed |
| US-8338544-B2 | Polymers functionalized with polyoxime compounds and methods for their manufacture | BRIDGESTONE CORPORATION (JP) | 2012-12-25 | — | — | US | disclosed |
| EP-2516475-A1 | POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE | Bridgestone Corporation (JP) | 2012-10-31 | — | — | EP | disclosed |
| US-20110152449-A1 | POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE | BRIDGESTONE CORPORATION (JP) | 2011-06-23 | — | — | US | disclosed |