Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 13/20 | 0.77 |
| ▸ | FLT4 | P35916 | 8/20 | 0.72 |
| ▸ | KDR | P35968 | 3/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20459318 | 0.87 | PTK2 (0.84) | PTK2FLT4KDR | |
| SCHEMBL12478131 | 0.87 | PTK2 (1.00) | PTK2FLT4KDR | |
| SCHEMBL12477968 | 0.84 | PTK2 (1.00) | PTK2FLT4KDR | |
| SCHEMBL15502384 | 0.83 | FLT4 (1.00) | PTK2FLT4KDR | |
| SCHEMBL15524366 | 0.83 | PTK2 (0.83) | PTK2FLT4KDR | |
| SCHEMBL15506719 | 0.83 | FLT4 (0.95) | PTK2FLT4KDR | |
| SCHEMBL12478148 | 0.82 | PTK2 (1.00) | PTK2FLT4KDR | |
| SCHEMBL12478471 | 0.82 | PTK2 (1.00) | PTK2FLT4KDR | |
| SCHEMBL15506624 | 0.82 | FLT4 (1.00) | PTK2FLT4KDR | |
| SCHEMBL15506625 | 0.82 | FLT4 (1.00) | PTK2FLT4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675793-B1 | FAK INHIBITORS | CANCER THERAPEUTICS CRC PTY LTD (AU) | 2018-08-08 | — | — | EP | disclosed |