Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC1R | Q01726 | 9/20 | 0.68 |
| ▸ | MC4R | P32245 | 9/20 | 0.68 |
| ▸ | MC5R | P33032 | 1/20 | 0.39 |
| ▸ | MC3R | P41968 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | YAP1 | P46937 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1310136 | 1.00 | MC1R (0.68) | MC1RMC4RMC5RMC3RHDAC3 | |
| SCHEMBL1310055 | 1.00 | MC1R (0.68) | MC1RMC4RMC5RMC3RHDAC3 | |
| SCHEMBL2154559 | 0.95 | MC1R (0.62) | MC1RMC4RMC5RMC3RYAP1 | |
| SCHEMBL20450376 | 0.94 | MC1R (0.72) | MC1RMC4RMC5RMC3RHDAC3 | |
| SCHEMBL1312417 | 0.94 | MC1R (0.72) | MC1RMC4RMC5RMC3RHDAC3 | |
| SCHEMBL2154739 | 0.94 | MC1R (0.72) | MC1RMC4RMC5RMC3RHDAC3 | |
| SCHEMBL1310172 | 0.94 | MC1R (0.72) | MC1RMC4RMC5RMC3RHDAC3 | |
| SCHEMBL20450360 | 0.94 | MC1R (0.78) | MC1RMC4RMC5RMC3RHDAC3 | |
| SCHEMBL1310201 | 0.94 | MC1R (0.78) | MC1RMC4RMC5RMC3RHDAC3 | |
| SCHEMBL1310839 | 0.94 | MC1R (0.78) | MC1RMC4RMC5RMC3RHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342194-B1 | OXOAZETIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2018-08-08 | — | — | EP | claimed |