⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7919651 | 0.84 | TSHR (0.42) | — | |
| SCHEMBL8097395 | 0.80 | TSHR (0.46) | — | |
| SCHEMBL5053162 | 0.80 | TSHR (0.46) | — | |
| SCHEMBL12572880 | 0.80 | TSHR (0.31) | — | |
| SCHEMBL3193185 | 0.79 | — | — | |
| SCHEMBL3193176 | 0.79 | — | — | |
| SCHEMBL1453600 | 0.76 | — | — | |
| SCHEMBL7583573 | 0.76 | — | — | |
| SCHEMBL31141255 | 0.75 | — | — | |
| SCHEMBL29621395 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11634540-B2 | Polymeric alpha-hydroxy aldehyde and ketone reagents and conjugation method | NEKTAR THERAPEUTICS (US) | 2023-04-25 | — | — | US | disclosed |
| EP-3318580-B1 | AQUEOUS EMULSION COMPOSITION | KURARAY CO (JP) | 2022-12-28 | — | — | EP | disclosed |
| US-20220081512-A1 | POLYMERIC ALPHA-HYDROXY ALDEHYDE AND KETONE REAGENTS AND CONJUGATION METHOD | NEKTAR THERAPEUTICS (US) | 2022-03-17 | — | — | US | disclosed |
| EP-2331139-A2 | POLYMERIC ALPHA-HYDROXY ALDEHYDE AND KETONE REAGENTS AND CONJUGATION METHOD | Nektar Therapeutics (US) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010030366-A2 | POLYMERIC ALPHA-HYDROXY ALDEHYDE AND KETONE REAGENTS AND CONJUGATION METHOD | NEKTAR THERAPEUTICS (US) | 2010-03-18 | — | — | WO | disclosed |
| US-5866684-A | Peptidyl inhibitors of viral proteases | HOFFMANN-LA ROCHE INC. (US) | 1999-02-02 | — | — | US | disclosed |
| EP-0287956-B1 | Process for the preparation of 5-formylevalerianic acid esters or the corresponding acetals | BASF AG (DE) | 1993-11-24 | — | — | EP | disclosed |
| EP-0287956-A2 | Process for the preparation of 5-formylevalerianic acid esters or the corresponding acetals | BASF Aktiengesellschaft (DE) | 1988-10-26 | — | — | EP | disclosed |