Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 11/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.49 |
| ▸ | USP2 | O75604 | 6/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 6/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.41 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL485117 | 0.83 | CYP2D6 (0.51) | CYP3A4CYP2D6USP2CYP1A2ALDH1A1 | |
| SCHEMBL16730388 | 0.81 | CYP3A4 (0.43) | CYP3A4CYP2D6USP2CYP1A2CYP2C19 | |
| SCHEMBL24227415 | 0.81 | USP2 (0.46) | CYP3A4CYP2D6USP2CYP1A2ALDH1A1 | |
| SCHEMBL31276695 | 0.80 | CYP2D6 (0.54) | CYP3A4CYP2D6USP2CYP1A2ALDH1A1 | |
| SCHEMBL13050665 | 0.79 | CYP2D6 (0.63) | CYP3A4CYP2D6USP2CYP1A2ALDH1A1 | |
| SCHEMBL38664534 | 0.79 | CYP3A4 (0.60) | CYP3A4CYP2D6USP2CYP1A2ALDH1A1 | |
| SCHEMBL20791428 | 0.78 | CYP3A4 (0.73) | CYP3A4CYP2D6USP2CYP1A2ALDH1A1 | |
| SCHEMBL22914774 | 0.75 | KCNH2 (0.54) | CYP3A4CYP2D6USP2CYP1A2ALDH1A1 | |
| SCHEMBL14996492 | 0.75 | CYP3A4 (0.44) | CYP3A4CYP2D6USP2CYP1A2CYP2C19 | |
| SCHEMBL4617 | 0.75 | CYP3A4 (0.42) | CYP3A4CYP2D6USP2CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200048267-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2020-02-13 | — | — | US | disclosed |
| WO-2018141984-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2018-08-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200048267-A1 | OGA INHIBITOR COMPOUNDS | OGA, OGT, GRN | CYP3A4 4278/4885CYP2D6 4092/4885USP2 705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.