Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 20/20 | 0.51 |
| ▸ | CNR1 | P21554 | 11/20 | 0.45 |
| ▸ | CYP2C8 | P10632 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9892901 | 0.90 | CNR2 (0.46) | CNR2CNR1CYP2C8CYP2C19CYP2C9 | |
| SCHEMBL9892915 | 0.90 | CNR2 (0.49) | CNR2CNR1CYP2C8CYP2C19CYP2C9 | |
| SCHEMBL9892843 | 0.90 | CNR2 (0.51) | CNR2CNR1CYP2C8CYP2C19CYP2C9 | |
| SCHEMBL2568728 | 0.86 | CNR2 (0.54) | CNR2CNR1CYP2C8CYP2C19CYP2C9 | |
| SCHEMBL9892272 | 0.86 | CNR2 (0.54) | CNR2CNR1CYP2C8CYP2C19CYP2C9 | |
| SCHEMBL9892900 | 0.84 | CNR2 (0.60) | CNR2CNR1CYP2C8CYP2C19CYP2C9 | |
| SCHEMBL9892832 | 0.80 | CNR2 (0.47) | CNR2CNR1 | |
| SCHEMBL9892930 | 0.80 | CNR2 (0.56) | CNR2CNR1CYP2C8CYP2C19CYP2C9 | |
| SCHEMBL9892844 | 0.79 | CNR2 (0.44) | CNR2CNR1 | |
| SCHEMBL2580450 | 0.78 | CNR2 (0.55) | CNR2CNR1CYP2C8CYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443107-B1 | AZETIDINE 2 -CARBOXAMIDE DERIVATIVES WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INT (DE) | 2018-08-08 | — | — | EP | disclosed |