Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 20/20 | 0.90 |
| ▸ | CNR1 | P21554 | 14/20 | 0.90 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2126970 | 1.00 | CNR2 (0.90) | CNR2CNR1CYP2C8CYP2C19CYP2D6 | |
| SCHEMBL9893079 | 0.95 | CNR2 (1.00) | CNR2CNR1CYP2C8CYP2C19CYP2D6 | |
| SCHEMBL2574761 | 0.95 | CNR2 (1.00) | CNR2CNR1CYP2C8CYP2C19CYP2D6 | |
| SCHEMBL13257146 | 0.94 | CNR2 (0.95) | CNR2CNR1CYP2C8CYP2C19CYP2D6 | |
| SCHEMBL16254900 | 0.92 | CNR2 (0.80) | CNR2CNR1CYP2C8CYP2C19CYP2D6 | |
| SCHEMBL2575204 | 0.86 | CNR2 (0.74) | CNR2CNR1CYP2C8CYP2C19CYP2D6 | |
| SCHEMBL9892035 | 0.86 | CNR2 (0.74) | CNR2CNR1CYP2C8CYP2C19CYP2D6 | |
| SCHEMBL9892028 | 0.86 | CNR2 (0.74) | CNR2CNR1CYP2C8CYP2C19CYP2D6 | |
| SCHEMBL9892006 | 0.85 | CNR2 (0.72) | CNR2CNR1CYP2C8CYP2C19CYP2D6 | |
| SCHEMBL9892861 | 0.84 | CNR2 (0.66) | CNR2CNR1CYP2C8CYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443107-B1 | AZETIDINE 2 -CARBOXAMIDE DERIVATIVES WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INT (DE) | 2018-08-08 | — | — | EP | disclosed |