Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 5/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 4/20 | 0.40 |
| ▸ | HTR6 | P50406 | 8/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16956125 | 0.77 | HTR2C (0.74) | HTR2CPDK2PDK4HTR6 | |
| SCHEMBL2050443 | 0.77 | HSD17B10 (0.43) | HTR2CPDK2PDK4 | |
| SCHEMBL21163634 | 0.75 | HTR2C (0.46) | HTR2CPDK2PDK4HTR6 | |
| SCHEMBL930210 | 0.74 | HTR2C (0.48) | HTR2CPDK2PDK4NOTUM | |
| SCHEMBL2044125 | 0.74 | OPRL1 (0.37) | HTR2CPDK2PDK4NOTUM | |
| SCHEMBL23668202 | 0.74 | HTR2C (0.48) | HTR2CPDK2PDK4HTR6NOTUM | |
| SCHEMBL13898705 | 0.74 | HTR2C (0.48) | HTR2CPDK2PDK4HTR6PDK1 | |
| SCHEMBL21388492 | 0.74 | HTR2C (0.48) | HTR2CHTR6 | |
| SCHEMBL2049706 | 0.74 | HTR2C (0.48) | HTR2CPDK2PDK4HTR6NOTUM | |
| SCHEMBL19633961 | 0.74 | HTR2C (0.48) | HTR2CHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150336979-A1 | ISOMANNIDE DERIVATIVES AS INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | SANOFI (FR) | 2015-11-26 | — | — | US | disclosed |
| US-7964531-B2 | 3-phenoxy-4-pyridazinol derivatives and herbicidal composition containing the same | MITSUI CHEMICALS AGRO, INC. (JP) | 2011-06-21 | — | — | US | disclosed |
| US-20100041555-A1 | 3-Phenoxy-4-pyridazinol derivatives and herbicidal composition containing the same | MITSUI CHEMICALS AGRO, INC. (JP) | 2010-02-18 | — | — | US | disclosed |
| US-7608563-B2 | 3-phenoxy-4-pyridazinol derivatives and herbicide composition containing the same | MITSUI AGRO CHEMICALS, INC. (JP) | 2009-10-27 | — | — | US | disclosed |
| EP-1426365-B9 | 3-PHENOXY-4-PYRIDAZINOL DERIVATIVE AND HERBICIDE COMPOSITION CONTAINING THE SAME | MITSUI CHEMICALS AGRO INC (JP) | 2009-10-21 | — | — | EP | disclosed |
| EP-1426365-B1 | 3-PHENOXY-4-PYRIDAZINOL DERIVATIVE AND HERBICIDE COMPOSITION CONTAINING THE SAME | SANKYO AGRO CO LTD (JP) | 2009-07-15 | — | — | EP | disclosed |
| US-20050037925-A1 | 3-phenoxy-4-pyridazinol derivatives and herbicide composition containing the same | SANKYO AGRO COMPANY, LIMITED (JP) | 2005-02-17 | — | — | US | disclosed |
| EP-1426365-A1 | 3-PHENOXY-4-PYRIDAZINOL DERIVATIVE AND HERBICIDE COMPOSITION CONTAINING THE SAME | Sankyo Agro Company, Limited (JP) | 2004-06-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150336979-A1 | ISOMANNIDE DERIVATIVES AS INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | EPHX1, EPHX2, NR1H2 | HTR2C 3303/4885PDK2 1109/4885PDK4 1371/4885 |
| US-20100041555-A1 | 3-Phenoxy-4-pyridazinol derivatives and herbicidal composition containing the same | CBR3, DDT, CBR1 | HTR2C 434/4885PDK2 138/4885PDK4 216/4885 |
| US-20050037925-A1 | 3-phenoxy-4-pyridazinol derivatives and herbicide composition containing the same | CBR3, DDT, CHRM2 | HTR2C 634/4885PDK2 164/4885PDK4 154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.