Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.49 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.49 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.49 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.49 |
| ▸ | PNP | P00491 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28037851 | 0.85 | PNP (0.59) | PNPADORA2AADORA1CYP1A2CYP3A4 | |
| SCHEMBL5363128 | 0.79 | CYP1A2 (0.46) | PI4KAPI4K2BPI4K2API4KBPNP | |
| SCHEMBL17843613 | 0.75 | ADORA2A (0.46) | PI4KAPI4K2BPI4K2API4KBPNP | |
| SCHEMBL5072515 | 0.74 | PI4KA (0.51) | PI4KAPI4K2BPI4K2API4KBADORA3 | |
| SCHEMBL16486562 | 0.73 | PI4KA (0.41) | PI4KAPI4K2BPI4K2API4KBPARP1 | |
| SCHEMBL5357839 | 0.73 | PNP (0.42) | PI4KAPI4K2BPI4K2API4KBPNP | |
| SCHEMBL5358015 | 0.73 | PNP (0.42) | PI4KAPI4K2BPI4K2API4KBPNP | |
| Alcohol SCHEMBL28116206 | 0.73 | PNP (0.54) | PNP | |
| SCHEMBL27648253 | 0.73 | PNP (0.61) | PNPCYP2D6 | |
| SCHEMBL3453941 | 0.72 | PI4KA (0.54) | PI4KAPI4K2BPI4K2API4KBADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2510118-A2 | PREFERENTIAL AMPLIFICATION OF MRNA OVER DNA USING CHEMICALLY MODIFIED PRIMERS | Roche Diagniostics GmbH (DE) | 2012-10-17 | — | — | EP | claimed |
| CN-102639719-A | Preferential amplification of mRNA over DNA using chemically modified primers | ROCHE DIAGNOSTICS GMBH | 2012-08-15 | — | — | CN | claimed |
| CN-102186996-A | Improved allele-specific amplification | ROCHE DIAGNOSTICS GMBH | 2011-09-14 | — | — | CN | claimed |
| WO-2011069676-A2 | PREFERENTIAL AMPLIFICATION OF MRNA OVER DNA USING CHEMICALLY MODIFIED PRIMERS | ROCHE DIAGNOSTICS GMBH (DE) | 2011-06-16 | — | — | WO | claimed |
| EP-1951895-A1 | ASSOCIATION OF PDE4D ALLELIC VARIANTS WITH STROKE | BOEHRINGER MANNHEIM GMBH (DE) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007048574-A1 | ASSOCIATION OF PDE4D ALLELIC VARIANTS WITH STROKE | ROCHE DIAGNOSTICS GMBH (DE) | 2007-05-03 | — | — | WO | disclosed |
| EP-1611254-A2 | COMPOSITIONS AND METHODS FOR DETECTING CERTAIN FLAVIVIRUSES, INCLUDING MEMBERS OF THE JAPANESE ENCEPHALITIS VIRUS SEROGROUP | Roche Diagnostics GmbH (DE) | 2006-01-04 | — | — | EP | disclosed |
| WO-2004092412-A2 | COMPOSITIONS AND METHODS FOR DETECTING CERTAIN FLAVIVIRUSES, INCLUDING MEMBERS OF THE JAPANESE ENCEPHALITIS VIRUS SEROGROUP | ROCHE DIAGNOSTICS GMBH (DE) | 2004-10-28 | — | — | WO | disclosed |