Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 20/20 | 0.86 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20458944 | 0.95 | PIK3CD (0.85) | PIK3CD | |
| SCHEMBL788714 | 0.93 | PIK3CD (1.00) | PIK3CD | |
| SCHEMBL20458956 | 0.90 | PIK3CD (0.91) | PIK3CD | |
| SCHEMBL789044 | 0.89 | PIK3CD (1.00) | PIK3CD | |
| SCHEMBL788803 | 0.88 | PIK3CD (1.00) | PIK3CD | |
| SCHEMBL788439 | 0.88 | PIK3CD (1.00) | PIK3CD | |
| SCHEMBL788306 | 0.86 | PIK3CD (0.86) | PIK3CD | |
| SCHEMBL788219 | 0.85 | PIK3CD (1.00) | PIK3CD | |
| SCHEMBL15464148 | 0.85 | PIK3CD (1.00) | PIK3CD | |
| SCHEMBL10117582 | 0.84 | PIK3CD (0.82) | PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616442-B1 | INHIBITORS OF PI3K-DELTA AND METHODS OF THEIR USE AND MANUFACTURE | EXELIXIS INC (US) | 2018-08-08 | — | — | EP | disclosed |