Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 9/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21547438 | 0.84 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3KCNH2CYP1A2 | |
| SCHEMBL12313210 | 0.84 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3KCNH2CYP1A2 | |
| SCHEMBL21525966 | 0.84 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3KCNH2CYP1A2 | |
| SCHEMBL11915419 | 0.84 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3KCNH2CYP1A2 | |
| SCHEMBL21525963 | 0.84 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3KCNH2CYP1A2 | |
| SCHEMBL11911765 | 0.84 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3KCNH2CYP1A2 | |
| Hydrochloric Acid SCHEMBL21525949 | 0.83 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3KCNH2CYP1A2 | |
| SCHEMBL4711875 | 0.80 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3KCNH2CYP1A2 | |
| Hydrochloric Acid SCHEMBL11076402 | 0.79 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3KCNH2CYP1A2 | |
| SCHEMBL13907459 | 0.77 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3KCNH2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2719384-B1 | Novel 1-naphthyl-3-azabicyclo[3.1.0]hexanes:preparation and use to treat neuropsychiatric disorders | OTSUKA AMERICA PHARMACEUTICAL INC (US) | 2018-08-08 | — | — | EP | disclosed |