Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 19/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 19/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21726293 | 0.81 | SLC6A4 (0.70) | SLC6A4SLC6A3SLC6A2GAACASP1 | |
| SCHEMBL7901520 | 0.79 | SLC6A4 (0.59) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL17708138 | 0.78 | SLC6A4 (0.62) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL5086489 | 0.77 | SLC6A4 (1.00) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL3521286 | 0.76 | SLC6A4 (1.00) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL17999736 | 0.76 | SLC6A4 (1.00) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL3517982 | 0.76 | SLC6A4 (1.00) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL17999738 | 0.76 | SLC6A4 (1.00) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL20459051 | 0.74 | SLC6A4 (0.84) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL3520312 | 0.73 | SLC6A4 (1.00) | SLC6A4SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2719384-B1 | Novel 1-naphthyl-3-azabicyclo[3.1.0]hexanes:preparation and use to treat neuropsychiatric disorders | OTSUKA AMERICA PHARMACEUTICAL INC (US) | 2018-08-08 | — | — | EP | disclosed |