Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 18/20 | 0.61 |
| ▸ | FLT4 | P35916 | 3/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14643156 | 0.90 | PTK2 (0.76) | PTK2FLT4 | |
| SCHEMBL14576658 | 0.89 | PTK2 (0.65) | PTK2FLT4 | |
| SCHEMBL12478987 | 0.80 | PTK2 (0.83) | PTK2 | |
| SCHEMBL14643155 | 0.79 | SYK (0.47) | PTK2 | |
| SCHEMBL14643093 | 0.77 | PTK2 (0.82) | PTK2FLT4 | |
| SCHEMBL14576350 | 0.76 | PTK2 (1.00) | PTK2 | |
| SCHEMBL15598564 | 0.76 | PTK2 (0.71) | PTK2FLT4 | |
| SCHEMBL12478687 | 0.76 | PTK2 (0.47) | PTK2FLT4 | |
| SCHEMBL27949158 | 0.76 | PTK2 (0.79) | PTK2FLT4 | |
| SCHEMBL14643094 | 0.76 | PTK2 (0.84) | PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675793-B1 | FAK INHIBITORS | CANCER THERAPEUTICS CRC PTY LTD (AU) | 2018-08-08 | — | — | EP | disclosed |