Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 20/20 | 0.84 |
| ▸ | PIM3 | Q86V86 | 20/20 | 0.84 |
| ▸ | PIM2 | Q9P1W9 | 20/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20460029 | 0.99 | PIM1 (0.83) | PIM1PIM3PIM2 | |
| SCHEMBL15400474 | 0.92 | PIM1 (1.00) | PIM1PIM3PIM2 | |
| SCHEMBL15401151 | 0.91 | PIM1 (1.00) | PIM1PIM3PIM2 | |
| SCHEMBL15401096 | 0.90 | PIM1 (1.00) | PIM1PIM3PIM2 | |
| SCHEMBL15401172 | 0.89 | PIM1 (1.00) | PIM1PIM3PIM2 | |
| SCHEMBL15400838 | 0.89 | PIM1 (1.00) | PIM1PIM3PIM2 | |
| SCHEMBL15399993 | 0.88 | PIM1 (1.00) | PIM1PIM3PIM2 | |
| SCHEMBL15399991 | 0.88 | PIM1 (1.00) | PIM1PIM3PIM2 | |
| SCHEMBL15401602 | 0.88 | PIM1 (1.00) | PIM1PIM3PIM2 | |
| SCHEMBL15400492 | 0.86 | PIM1 (1.00) | PIM1PIM3PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2867232-B1 | 5-AZAINDAZOLE COMPOUNDS AND METHODS OF USE | HOFFMANN LA ROCHE (CH) | 2018-08-08 | — | — | EP | disclosed |